Postdoctoral Research Fellow
University Health Network
Toronto, Ontario, Canada
13d ago

Status : Temporary Full-Time (2 years)

A Senior is required to investigate cell therapy applications with focus on Osteoarthritis. Specifically, the Postdoctoral Fellow will be involved in evaluating the basic immunobiology of human monocytes / macrophages and mesechymal stromal cells (MSCs) in vitro and in vivo.

Experiments may also be related to investigating leukocyte phenotypes and cytokine profiles in a future Phase II clinical trial.

The candidate will be supervised by Principal Investigator, who is a translational scientist, leading Canada’s first cell therapy trial in Osteoarthritis and has been involved in translating over 10 cell and gene therapy research projects into the clinic.

Candidates should have strong research background in immunology and human cell culture experience. Molecular biology skills are also desired.

This position is a great opportunity for a talented scientist to have the opportunity to be involved in ground breaking cell therapy clinical trials, immunomodulation, creation of new cell therapies and working closely with orthopedic surgeons to handle patient samples and develop new approaches to treat diseases.

The lab also has an interest in working with the orthopedic surgeons to develop novel cellular biomarkers.

Qualifications :

  • Ph.D within the past 5 years in a related field with extensive experience in cell therapy or general immunology
  • Expertise in immune cell functional assays : T cell proliferation, immunophenotyping (flow cytometry), multiplex assays / ELISAs, RT-PCR, molecular biology
  • Hands-on expertise in primary human cell culture and isolation
  • Knowledge of MSCs and animal models would be an asset
  • Background in macrophage immunology and osteoarthritis are definite assets
  • Statistical knowledge is an asset
  • If you are interested in making your contribution at UHN, please apply on-line. You will be asked to copy and paste as well as attach your resume and covering letter.

    You will also be required to complete some initial screening questions.

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